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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   STK16 Antibody (clone M2)   

STK16 Antibody (clone M2)

Mouse Monoclonal Antibody

     
  • WB - STK16 Antibody (clone M2) ALS13444
    Western blot of STK16 expression in transfected 293T cell line by STK16 monoclonal antibody,...
  • WB - STK16 Antibody (clone M2) ALS13444
    STK16 monoclonal antibody, clone M2 Western blot of STK16 expression in A-431.
  • IHC - STK16 Antibody (clone M2) ALS13444
    Anti-STK16 antibody IHC of human adrenal.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, RNAi
Primary Accession O75716
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names M2
Calculated MW 35kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 8576
Other Names Serine/threonine-protein kinase 16, 2.7.11.1, Myristoylated and palmitoylated serine/threonine-protein kinase, MPSK, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, Tyrosine-protein kinase STK16, 2.7.10.2, hPSK, STK16, MPSK1, PKL12, TSF1
Reconstitution & Storage Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsSTK16 Antibody (clone M2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STK16
Synonyms MPSK1, PKL12, TSF1
Function Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
Cellular Location Cytoplasm, perinuclear region. Membrane; Lipid-anchor. Note=Associates with Golgi and Golgi-derived vesicles.
Tissue Location Ubiquitously expressed at very low levels.
Research Areas
Citations (0)

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Background

Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.

References

Ligos J.M.,et al.Biochem. Biophys. Res. Commun. 249:380-384(1998).
Berson A.E.,et al.Biochem. Biophys. Res. Commun. 259:533-538(1999).
Ohta S.,et al.Biochem. J. 350:395-404(2000).
Wabakken T.K.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Stairs D.B.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.

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$ 450.00
Cat# ALS13444
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