CDC123 Antibody (clone 4B9)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | O75794 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 4B9 |
Calculated MW | 39kDa |
Dilution | IHC-P (5 µg/ml) |
Gene ID | 8872 |
---|---|
Other Names | Cell division cycle protein 123 homolog, Protein D123, HT-1080, PZ32, CDC123, C10orf7, D123 |
Reconstitution & Storage | Store at -20°C. Aliquot to avoid freeze/thaw cycles. |
Precautions | CDC123 Antibody (clone 4B9) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CDC123 |
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Synonyms | C10orf7, D123 |
Function | ATP-dependent protein-folding chaperone for the eIF2 complex (PubMed:35031321, PubMed:37507029). Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (By similarity). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q62834}. |
Tissue Location | Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Required for S phase entry of the cell cycle.
References
Okuda A.,et al.Exp. Cell Res. 223:242-249(1996).
Onisto M.,et al.Exp. Cell Res. 242:451-459(1998).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 429:375-381(2004).
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