|Application ||WB, IHC-P, IF, E|
|Dilution||IF (10 µg/ml), IHC-P (5 µg/ml), WB (1:500-1:1000)|
|Other Names||Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1, CYTH1, D17S811E, PSCD1|
|Reconstitution & Storage||Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||CYTH1 / Cytohesin-1 Antibody (clone 1D6) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.|
|Cellular Location||Cell membrane; Peripheral membrane protein Cytoplasm, cytosol|
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Provided below are standard protocols that you may find useful for product applications.
Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.
Liu L.,et al.Biochim. Biophys. Acta 1132:75-78(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Ogasawara M.,et al.J. Biol. Chem. 275:3221-3230(2000).
Vitale N.,et al.J. Biol. Chem. 275:21331-21339(2000).
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