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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   CD38 Antibody (clone HIT2)   

CD38 Antibody (clone HIT2)

Mouse Monoclonal Antibody

     
  • IHC - CD38 Antibody (clone HIT2) ALS13467
    Anti-CD38 antibody IHC of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IHC-Fr, Flo
Primary Accession P28907
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names HIT2
Calculated MW 34kDa
Dilution IHC-Fr, IHC-P (20 µg/ml), WB (2 µg/ml)
Additional Information
Gene ID 952
Other Names ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, 3.2.2.6, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2.4.99.20, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, ADPRC 1, Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10, CD38, CD38
Target/Specificity Reacts with CD38 (T10), a 45 kD type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes; it is an antigenic marker of lymphoid cells.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsCD38 Antibody (clone HIT2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD38
Function Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Cellular Location Membrane; Single-pass type II membrane protein
Tissue Location Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
Research Areas
Citations (0)

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Background

Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

References

Jackson D.G.,et al.J. Immunol. 144:2811-2815(1990).
Nata K.,et al.Gene 186:285-292(1997).
States D.J.,et al.Trends Biochem. Sci. 17:495-495(1992).
Takasawa S.,et al.J. Biol. Chem. 268:26052-26054(1993).
Tohgo A.,et al.J. Biol. Chem. 269:28555-28557(1994).

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$ 395.00
Cat# ALS13467
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