|Application ||IHC-P, ICC|
|Reactivity||Human, Mouse, Rat, Pig|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Kinesin-1 heavy chain, Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC, KIF5B, KNS, KNS1|
|Target/Specificity||Recognizes heavy chain of conventional kinesin associated with vesicles and with lower affinity with denatured molecule. It stains Western blots of kinesin-enriched preparations. Epitope mapping (by limited proteolysis of partially purified porcine k ...|
|Reconstitution & Storage||Store at 4°C. Do not freeze.|
|Precautions||Kinesin Heavy Chain / KIF5B Antibody (clone KN-03) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.|
|Cellular Location||Cytoplasm, cytoskeleton. Note=Uniformly distributed between soma and neurites in hippocampal neurons.|
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Provided below are standard protocols that you may find useful for product applications.
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.
Navone F.,et al.J. Cell Biol. 117:1263-1275(1992).
Deloukas P.,et al.Nature 429:375-381(2004).
Su Q.,et al.Nat. Cell Biol. 6:941-953(2004).
Boucrot E.,et al.Science 308:1174-1178(2005).
Olsen J.V.,et al.Cell 127:635-648(2006).
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