|Application ||WB, IHC-P, E, IHC-Fr|
|Reactivity||Human, Rat, Pig|
|Dilution||IHC-P (10 µg/ml), WB (1 µg/ml),|
|Other Names||Neurofilament heavy polypeptide, NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein, NEFH, KIAA0845, NFH|
|Target/Specificity||The antibody NF-05 recognizes a nonphosphorylated epitope of neurofilament heavy protein (NF-H), a 210 kD intracellular structural protein of Intermediate Filament Proteins family. NF-H is mainly expressed in the central and peripheral nervous system ...|
|Reconstitution & Storage||Store at 4°C. Do not freeze.|
|Precautions||NEFH / NF-H Antibody (clone NF-05) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins.|
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Provided below are standard protocols that you may find useful for product applications.
Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins.
Lees J.F.,et al.EMBO J. 7:1947-1955(1988).
Zhu Y.,et al.Beijing Yi Ke Da Xue Xue Bao 31:531-531(1999).
Nagase T.,et al.DNA Res. 5:355-364(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham I.,et al.Nature 402:489-495(1999).
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