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LST1 Antibody (clone LST1/02)

Mouse Monoclonal Antibody

     
  • IHC - LST1 Antibody (clone LST1/02) ALS13470
    Anti-LST1 antibody IHC of human testis.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC, IP
Primary Accession O00453
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names LST1/02
Calculated MW 11kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 7940
Other Names Leukocyte-specific transcript 1 protein, Protein B144, LST1, B144
Target/Specificity The antibody LST1/02 reacts with an extracellular epitope of LST1, an approximately 6-11 kD protein expressed as various transmembrane or soluble forms. LST1 is found predominantly on monocytes and dendritic cells. It migrates on SDS PAGE gels as app ...
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsLST1 Antibody (clone LST1/02) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LST1
Synonyms B144
Function Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
Cellular Location Membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein Endomembrane system; Single-pass membrane protein. Note=Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm
Tissue Location Expressed in lung, tonsil, thymus, placenta, kidney, fetal spleen, fetal liver and brain
Research Areas
Citations (0)

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Background

Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.

References

Holzinger I.,et al.Immunogenetics 42:315-322(1995).
de Baey A.,et al.Genomics 45:591-600(1997).
Rollinger-Holzinger I.,et al.J. Immunol. 164:3169-3176(2000).
Xie T.,et al.Genome Res. 13:2621-2636(2003).
Shiina S.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS13470
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