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LST1 Antibody (clone LST1/02)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, ICC, IP |
|---|---|
| Primary Accession | O00453 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | LST1/02 |
| Calculated MW | 11kDa |
| Dilution | IHC-P (10 µg/ml) |
| Gene ID | 7940 |
|---|---|
| Other Names | Leukocyte-specific transcript 1 protein, Protein B144, LST1, B144 |
| Target/Specificity | The antibody LST1/02 reacts with an extracellular epitope of LST1, an approximately 6-11 kD protein expressed as various transmembrane or soluble forms. LST1 is found predominantly on monocytes and dendritic cells. It migrates on SDS PAGE gels as app ... |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | LST1 Antibody (clone LST1/02) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LST1 |
|---|---|
| Synonyms | B144 |
| Function | Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation. |
| Cellular Location | Membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Note=Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm |
| Tissue Location | Expressed in lung, tonsil, thymus, placenta, kidney, fetal spleen, fetal liver and brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
References
Holzinger I.,et al.Immunogenetics 42:315-322(1995).
de Baey A.,et al.Genomics 45:591-600(1997).
Rollinger-Holzinger I.,et al.J. Immunol. 164:3169-3176(2000).
Xie T.,et al.Genome Res. 13:2621-2636(2003).
Shiina S.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
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