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GRB2 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - GRB2 Antibody (C-Terminus) ALS13474
    Anti-GRB2 antibody IHC of human brain, cerebellum.
    detail
  • IHC - GRB2 Antibody (C-Terminus) ALS13474
    Anti-GRB2 antibody IHC of human brain, cortex.
    detail
  • IHC - GRB2 Antibody (C-Terminus) ALS13474
    Anti-GRB2 antibody IHC of human colon, myenteric plexus.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P62993
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 25kDa
Dilution IHC-P (10 µg/ml), WB (1 µg/ml),
Additional Information
Gene ID 2885
Other Names Growth factor receptor-bound protein 2, Adapter protein GRB2, Protein Ash, SH2/SH3 adapter GRB2, GRB2, ASH
Target/Specificity The polyclonal antibody recognizes Grb2, a highly conserved approximately 26 kD adaptor protein. The immunogen has 100% identity between man, cow, rat and mouse.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsGRB2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRB2
Synonyms ASH
Function Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
Cellular Location Nucleus. Cytoplasm. Endosome Golgi apparatus {ECO:0000250|UniProtKB:Q60631}
Research Areas
Citations (0)
citation

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Background

Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.

References

Lowenstein E.J.,et al.Cell 70:431-442(1992).
Matuoka K.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:9015-9019(1992).
Fath I.,et al.Science 264:971-974(1994).
Bochmann H.,et al.Genomics 56:203-207(1999).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.

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$ 467.50
Cat# ALS13474
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