|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (1 µg/ml),|
|Other Names||Growth factor receptor-bound protein 2, Adapter protein GRB2, Protein Ash, SH2/SH3 adapter GRB2, GRB2, ASH|
|Target/Specificity||The polyclonal antibody recognizes Grb2, a highly conserved approximately 26 kD adaptor protein. The immunogen has 100% identity between man, cow, rat and mouse.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||GRB2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.|
|Cellular Location||Nucleus. Cytoplasm. Endosome. Golgi apparatus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
Lowenstein E.J.,et al.Cell 70:431-442(1992).
Matuoka K.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:9015-9019(1992).
Fath I.,et al.Science 264:971-974(1994).
Bochmann H.,et al.Genomics 56:203-207(1999).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
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