GRB2 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | P62993 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 25kDa |
Dilution | IHC-P (10 µg/ml), WB (1 µg/ml), |
Gene ID | 2885 |
---|---|
Other Names | Growth factor receptor-bound protein 2, Adapter protein GRB2, Protein Ash, SH2/SH3 adapter GRB2, GRB2, ASH |
Target/Specificity | The polyclonal antibody recognizes Grb2, a highly conserved approximately 26 kD adaptor protein. The immunogen has 100% identity between man, cow, rat and mouse. |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | GRB2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GRB2 |
---|---|
Synonyms | ASH |
Function | Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. |
Cellular Location | Nucleus. Cytoplasm. Endosome Golgi apparatus {ECO:0000250|UniProtKB:Q60631} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
References
Lowenstein E.J.,et al.Cell 70:431-442(1992).
Matuoka K.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:9015-9019(1992).
Fath I.,et al.Science 264:971-974(1994).
Bochmann H.,et al.Genomics 56:203-207(1999).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
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