|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (1 µg/ml),|
|Other Names||Growth factor receptor-bound protein 2, Adapter protein GRB2, Protein Ash, SH2/SH3 adapter GRB2, GRB2, ASH|
|Target/Specificity||The polyclonal antibody recognizes Grb2, a highly conserved approximately 26 kD adaptor protein. The immunogen has 100% identity between man, cow, rat and mouse.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||GRB2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.|
|Cellular Location||Nucleus. Cytoplasm. Endosome. Golgi apparatus|
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Provided below are standard protocols that you may find useful for product applications.
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
Lowenstein E.J.,et al.Cell 70:431-442(1992).
Matuoka K.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:9015-9019(1992).
Fath I.,et al.Science 264:971-974(1994).
Bochmann H.,et al.Genomics 56:203-207(1999).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
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