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AG3 / AGR3 Antibody (clone AGR3.1)

Mouse Monoclonal Antibody

     
  • IHC - AG3 / AGR3 Antibody (clone AGR3.1) ALS13476
    Anti-AGR3 antibody IHC of human kidney.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC, IHC-Fr
Primary Accession Q8TD06
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names AGR3.1
Calculated MW 19kDa
Dilution IHC-Fr (1 µg/ml), IHC-P (10 µg/ml), WB (1 µg/ml)
Additional Information
Gene ID 155465
Other Names Anterior gradient protein 3 homolog, AG-3, AG3, hAG-3, Breast cancer membrane protein 11, AGR3, BCMP11
Target/Specificity The antibody AGR3.1 recognizes the epitope HETTDKNLS within the AGR3 (AG3) protein (19-20 kD); a secreted cytoplasmic protein which can serve as a marker of carcinogenesis.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsAG3 / AGR3 Antibody (clone AGR3.1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGR3
Synonyms BCMP11, PDIA18
Function Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells.
Cellular Location Endoplasmic reticulum Note=Found in the cytoplasm, which could include the endoplasmic reticulum.
Tissue Location Expressed in the lung, in the ciliated cells of the airway epithelium (PubMed:25751668). Expression increased with differentiation of airway epithelial cells (PubMed:25751668) Not detected in the mucous cells (PubMed:25751668). Expressed in ciliated cells in the oviduct (PubMed:26170690). Also detected in stomach, colon, prostate and liver (PubMed:25751668). Expressed in breast, ovary, prostate and liver cancer (PubMed:26170690) Expression is associated with the level of differentiation of breast cancer (at protein level) (PubMed:26170690)
Research Areas
Citations (0)

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References

Adam P.J.,et al.J. Biol. Chem. 278:6482-6489(2003).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Scherer S.W.,et al.Science 300:767-772(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).

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$ 395.00
Cat# ALS13476
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