|Application ||WB, IHC-P, ICC, IP|
|Reactivity||Human, Rat, Pig|
|Dilution||ICC (1-4 µg/ml), IHC-P (10 µg/ml), WB (1-2 µg/ml)|
|Other Names||Glial fibrillary acidic protein, GFAP, GFAP|
|Target/Specificity||The antibody GA-5 reacts with GFAP, the principal marker of astroglial cells in the central nervous system, which is specifically expressed in satellite cells in peripheral ganglia and in non myelinating Schwann cells in peripheral nerves. The GFAP p ...|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||GFAP Antibody (clone GA-5) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.|
|Cellular Location||Cytoplasm. Note=Associated with intermediate filaments|
|Tissue Location||Expressed in cells lacking fibronectin.|
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Provided below are standard protocols that you may find useful for product applications.
GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Reeves S.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:5178-5182(1989).
Brenner M.,et al.Brain Res. Mol. Brain Res. 7:277-286(1990).
Bongcam-Rudloff E.,et al.Cancer Res. 51:1553-1560(1991).
Kumanishi T.,et al.Acta Neuropathol. 83:569-578(1992).
Isaacs A.,et al.Genomics 51:152-154(1998).
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