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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   SELPLG / PSGL-1 / CD162 Antibody (clone TC2)   

SELPLG / PSGL-1 / CD162 Antibody (clone TC2)

Mouse Monoclonal Antibody

     
  • IHC - SELPLG / PSGL-1 / CD162 Antibody (clone TC2) ALS13479
    Anti-SELPLG / CD162 antibody IHC of human tonsil.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, Flo
Primary Accession Q14242
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names TC2
Calculated MW 43kDa
Dilution Flo (1.5-2.5 µg/ml), IHC-P (10 µg/ml),
Additional Information
Gene ID 6404
Other Names P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162, SELPLG
Target/Specificity The antibody TC2 reacts with CD162, a 220 kD type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes; it is also expressed on a ...
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsSELPLG / PSGL-1 / CD162 Antibody (clone TC2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SELPLG
Function A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed on neutrophils, monocytes and most lymphocytes
Research Areas
Citations (0)

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Background

A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.

References

Veldman G.M.,et al.J. Biol. Chem. 270:16470-16475(1995).
Sako D.,et al.Cell 75:1179-1186(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Moore K.L.,et al.J. Biol. Chem. 269:23318-23327(1994).

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$ 395.00
Cat# ALS13479
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