CRIM1 Antibody (clone 6E4)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q9NZV1 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 6E4 |
Calculated MW | 114kDa |
Dilution | IHC-P (2.5 µg/ml) |
Gene ID | 51232 |
---|---|
Other Names | Cysteine-rich motor neuron 1 protein, CRIM-1, Cysteine-rich repeat-containing protein S52, Processed cysteine-rich motor neuron 1 protein, CRIM1, S52 |
Reconstitution & Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | CRIM1 Antibody (clone 6E4) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CRIM1 |
---|---|
Synonyms | S52 |
Function | May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface. |
Cellular Location | [Processed cysteine-rich motor neuron 1 protein]: Secreted |
Tissue Location | Expressed in pancreas, kidney, skeletal muscle, lung, placenta, brain, heart, spleen, liver and small intestine Expressed in blood vessels (at protein level) |
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Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface.
References
Kolle G.V.,et al.Mech. Dev. 90:181-193(2000).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Wilkinson L.,et al.J. Biol. Chem. 278:34181-34188(2003).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
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