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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AKR1B10 Antibody (clone 1A6)   

AKR1B10 Antibody (clone 1A6)

Mouse Monoclonal Antibody

     
  • WB - AKR1B10 Antibody (clone 1A6) ALS13493
    AKR1B10 monoclonal antibody, clone 1A6 Western blot of AKR1B10 expression in HepG2.
  • IF - AKR1B10 Antibody (clone 1A6) ALS13493
    Immunofluorescence of monoclonal antibody to AKR1B10 on HeLa cell (antibody concentration 10 ug/ml).
  • IHC - AKR1B10 Antibody (clone 1A6) ALS13493
    Anti-AKR1B10 antibody IHC of human small intestine.
  • IHC - AKR1B10 Antibody (clone 1A6) ALS13493
    Anti-AKR1B10 antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession O60218
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1A6
Calculated MW 36kDa
Dilution IF (10 µg/ml), IHC-P (5 µg/ml),
Additional Information
Gene ID 57016
Other Names Aldo-keto reductase family 1 member B10, 1.1.1.-, ARL-1, Aldose reductase-like, Aldose reductase-related protein, ARP, hARP, Small intestine reductase, SI reductase, AKR1B10, AKR1B11
Reconstitution & Storage Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsAKR1B10 Antibody (clone 1A6) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKR1B10
Synonyms AKR1B11
Function Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
Cellular Location Lysosome. Secreted. Note=Secreted through a lysosome-mediated non-classical pathway
Tissue Location Found in many tissues. Highly expressed in small intestine, colon and adrenal gland
Research Areas
Citations (0)

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Background

Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.

References

Cao D.,et al.J. Biol. Chem. 273:11429-11435(1998).
Hyndman D.J.,et al.Biochim. Biophys. Acta 1399:198-202(1998).
Heringlake S.,et al.Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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$ 450.00
Cat# ALS13493
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