|Application ||WB, IHC-P, IF|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (0.5-1 µg/ml),|
|Other Names||Disks large-associated protein 2, DAP-2, PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, SAPAP2, DLGAP2, DAP2|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||DLGAP2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.|
|Cellular Location||Cell membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density Cell junction, synapse. Note=Postsynaptic density of neuronal cells.|
|Tissue Location||Expressed in brain and kidney.|
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May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
Ranta S.,et al.Eur. J. Hum. Genet. 8:381-384(2000).
Nusbaum C.,et al.Nature 439:331-335(2006).
Mural R.J.,et al.Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
Satoh K.,et al.Genes Cells 2:415-424(1997).
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