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GOLM1 / GP73 / GOLPH2 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IF - GOLM1 / GP73 / GOLPH2 Antibody (Internal) ALS13538
    Immunofluorescence of GOLPH2 in rat brain tissue with GOLPH2 antibody at 20 ug/ml.
    detail
  • WB - GOLM1 / GP73 / GOLPH2 Antibody (Internal) ALS13538
    Western blot of GOLPH2 in rat brain tissue lysate with GOLPH2 antibody at (A) 0.25 and (B) 0.5...
    detail
  • IHC - GOLM1 / GP73 / GOLPH2 Antibody (Internal) ALS13538
    Anti-GOLM1 / GOLPH2 antibody IHC of human small intestine.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q8NBJ4
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 45kDa
Dilution IHC-P (5 µg/ml), WB (0.25-0.5 µg/ml),
Additional Information
Gene ID 51280
Other Names Golgi membrane protein 1, Golgi membrane protein GP73, Golgi phosphoprotein 2, GOLM1, C9orf155, GOLPH2
Target/Specificity Human GOLM1
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsGOLM1 / GP73 / GOLPH2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GOLM1
Synonyms C9orf155, GOLPH2
Function Unknown. Cellular response protein to viral infection.
Cellular Location Golgi apparatus, cis-Golgi network membrane; Single-pass type II membrane protein. Note=Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption
Tissue Location Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis) Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant- cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes.
Research Areas
Citations (0)
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Background

Unknown. Cellular response protein to viral infection.

References

Kladney R.D.,et al.Gene 249:53-65(2000).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Otsuki T.,et al.DNA Res. 12:117-126(2005).
Puri S.,et al.Traffic 3:641-653(2002).

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Discontinued
Cat# ALS13538
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