BAR / BFAR Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | Q9NZS9 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 53kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 51283 |
---|---|
Other Names | Bifunctional apoptosis regulator, RING finger protein 47, BFAR, BAR, RNF47 |
Target/Specificity | Human BFAR |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | BAR / BFAR Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BFAR |
---|---|
Synonyms | BAR, RNF47 |
Function | Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors. |
Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
Tissue Location | Expressed highly in brain, moderately in small intestine, weakly in testes and only faintly in liver and skeletal muscle. Not expressed in heart, kidney, lung and spleen |
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Provided below are standard protocols that you may find useful for product applications.
Background
Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors.
References
Zhang H.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:2597-2602(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Roth W.,et al.Cell Death Differ. 10:1178-1187(2003).
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