DCLK2 / DCAMKL2 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q8N568 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 84kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 166614 |
---|---|
Other Names | Serine/threonine-protein kinase DCLK2, 2.7.11.1, CaMK-like CREB regulatory kinase 2, CL2, CLICK-II, CLICK2, Doublecortin domain-containing protein 3B, Doublecortin-like and CAM kinase-like 2, Doublecortin-like kinase 2, DCLK2, DCAMKL2, DCDC3B, DCK2 |
Target/Specificity | Human DCLK2 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | DCLK2 / DCAMKL2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DCLK2 |
---|---|
Synonyms | DCAMKL2, DCDC3B, DCK2 |
Function | Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. |
Tissue Location | Expressed in the brain, heart and eyes. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity).
References
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Reiner O.,et al.BMC Genomics 7:188-188(2006).
Tuy F.P.D.,et al.Dev. Neurosci. 30:171-186(2008).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.