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ANAPC13 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IF - ANAPC13 Antibody (Internal) ALS13570
    Immunofluorescence of APC13 in Jurkat cells with APC13 antibody at 20 ug/ml.
  • WB - ANAPC13 Antibody (Internal) ALS13570
    Western blot of APC13 in Jurkat cell tissue lysate with APC13 antibody at 1 ug/ml in (A) the...
  • IHC - ANAPC13 Antibody (Internal) ALS13570
    Anti-ANAPC13 antibody IHC of human adrenal.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q9BS18
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 9kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 25847
Other Names Anaphase-promoting complex subunit 13, APC13, Cyclosome subunit 13, ANAPC13
Target/Specificity Human ANAPC13
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsANAPC13 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANAPC13
Function Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Cellular Location Nucleus.
Citations (0)

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Background

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

References

Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Schwickart M.,et al.Mol. Cell. Biol. 24:3562-3576(2004).
Dube P.,et al.Mol. Cell 20:867-879(2005).
Jin L.,et al.Cell 133:653-665(2008).
Chang L.,et al.Nature 513:388-393(2014).

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$ 395.00
Cat# ALS13570
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