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>   home   >   Products   >   Primary Antibodies   >   SUMO2 + SUMO3 Antibody (C-Terminus)   

SUMO2 + SUMO3 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

  • IF - SUMO2 + SUMO3 Antibody (C-Terminus) ALS13572
    Immunofluorescence of SUMO3 in mouse liver tissue with SUMO3 antibody at 20 ug/ml.
  • WB - SUMO2 + SUMO3 Antibody (C-Terminus) ALS13572
    Western blot of SUMO3 in mouse liver tissue lysate with SUMO3 antibody at (A) and (B) 2 ug/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P61956
Other Accession P55854
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 10871 Da
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 6613
Other Names Small ubiquitin-related modifier 2, SUMO-2, HSMT3, SMT3 homolog 2 {ECO:0000312|HGNC:HGNC:11125}, SUMO-3, Sentrin-2, Ubiquitin-like protein SMT3B, Smt3B, SUMO2 (HGNC:11125)
Target/Specificity Human SUMO2/3.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsSUMO2 + SUMO3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SUMO2 (HGNC:11125)
Function Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins (PubMed:18408734, PubMed:18538659, PubMed:21965678, PubMed:9556629). Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744).
Cellular Location Nucleus. Nucleus, PML body.
Tissue Location Broadly expressed.
Volume 50 µl
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$ 395.00
Cat# ALS13572
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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