PTCHD2 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q9P2K9 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 153kDa |
Dilution | IHC-P (5 µg/ml) |
Gene ID | 57540 |
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Other Names | Patched domain-containing protein 2, Protein dispatched homolog 3, PTCHD2, DISP3, KIAA1337 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | PTCHD2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DISP3 {ECO:0000303|PubMed:15645143, ECO:0000312|HGNC:HGNC:29251} |
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Function | Plays a role in neuronal proliferation and differentiation (PubMed:25281927). Plays a role in the accumulation of cellular cholesterol (By similarity). Involved in intracellular lipid droplet formation (PubMed:25281927). May contribute to cholesterol homeostasis in neuronal cells (By similarity). |
Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:B9U3F2}; Multi-pass membrane protein. Note=Predominantly localized to cholesterol-enriched domains within the membrane (PubMed:19179482). Localizes to cytoplasmic punctate vesicular structures (By similarity) {ECO:0000250|UniProtKB:B9U3F2, ECO:0000269|PubMed:19179482} |
Tissue Location | Expressed in brain and testis (PubMed:15645143). |
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Provided below are standard protocols that you may find useful for product applications.
References
Nagase T.,et al.DNA Res. 7:65-73(2000).
Gregory S.G.,et al.Nature 441:315-321(2006).
Rhodes S.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
Katoh Y.,et al.Int. J. Oncol. 26:551-556(2005).
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