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LASP1 Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - LASP1 Antibody (Internal) ALS13604
    Antibody (0.1 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer).
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q14847
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 30kDa
Dilution ELISA (1:32000), IHC-P (2.5-5 µg/ml), WB (1:32000)
Additional Information
Gene ID 3927
Other Names LIM and SH3 domain protein 1, LASP-1, Metastatic lymph node gene 50 protein, MLN 50, LASP1, MLN50
Target/Specificity Human LASP1.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsLASP1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LASP1
Synonyms MLN50
Function Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).
Cellular Location Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Note=Associated with the F- actin rich cortical cytoskeleton.
Research Areas
Citations (0)

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Background

Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).

References

Tomasetto C.L.,et al.Genomics 28:367-376(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
Tomasetto C.,et al.FEBS Lett. 373:245-249(1995).

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$ 395.00
Cat# ALS13604
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