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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GC / Vitamin D-Binding Protein Antibody   

GC / Vitamin D-Binding Protein Antibody

Rabbit Polyclonal Antibody

     
  • IHC - GC / Vitamin D-Binding Protein Antibody ALS13630
    Anti-GC / VDBP antibody IHC of human liver.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession P02774
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 53kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 2638
Other Names Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, GC
Target/Specificity Recognizes Vitamin D binding protein (VDBP), the major carrier protein of vitamin D that also transports components such as fatty acids and endotoxins and has an important role in the actin scavenging system. VDBP is a 52-58 kD plasma protein synthes ...
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsGC / Vitamin D-Binding Protein Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GC
Function Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.

References

Cooke N.E.,et al.J. Clin. Invest. 76:2420-2424(1985).
Yang F.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:7994-7998(1985).
Braun A.,et al.Biochim. Biophys. Acta 1216:385-394(1993).
Witke W.F.,et al.Genomics 16:751-754(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS13630
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