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Complement C9 Antibody

Rabbit Polyclonal Antibody

     
  • IF - Complement C9 Antibody ALS13652
    Immunofluorescence of methanol-fixed HepG2, using Complement C9 antibody at 1:200 dilution.
    detail
  • WB - Complement C9 Antibody ALS13652
    Sample (30 ug of whole cell lysate). A: Raji. 7.5% SDS PAGE. C9 antibody diluted at 1:500.
    detail
  • IHC - Complement C9 Antibody ALS13652
    Anti-C9 antibody IHC of human small intestine, vessels.
    detail
  • IHC - Complement C9 Antibody ALS13652
    Anti-C9 antibody IHC of human placenta.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, ICC
Primary Accession P02748
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 63kDa
Dilution ICC (1:100-1:200), IF (1:100-1:200), IHC-P (10 µg/ml), WB (1:500-1:3000) ,
Additional Information
Gene ID 735
Other Names Complement component C9, Complement component C9a, Complement component C9b, C9
Target/Specificity Human Complement C9.
Reconstitution & Storage Aliquot and store at -20°C. Minimize freezing and thawing.
PrecautionsComplement C9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name C9
Function Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells (PubMed:9634479, PubMed:9212048, PubMed:26841934). C9 is the pore-forming subunit of the MAC (PubMed:4055801, PubMed:26841934, PubMed:30111885).
Cellular Location Secreted. Target cell membrane; Multi-pass membrane protein. Note=Secreted as soluble monomer Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore
Tissue Location Plasma (at protein level).
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.

References

Stanley K.K.,et al.EMBO J. 4:375-382(1985).
Discipio R.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 81:7298-7302(1984).
Marazziti D.,et al.Biochemistry 27:6529-6534(1988).
Witzel-Schloemp K.,et al.Immunogenetics 48:144-147(1998).
DiScipio R.G.,et al.J. Biol. Chem. 260:14802-14809(1985).

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$ 467.50
Cat# ALS13652
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