|Application ||WB, IHC-P, E|
|Dilution||IHC-P (1:50), WB (1:1000),|
|Other Names||Antithrombin-III, ATIII, Serpin C1, SERPINC1, AT3|
|Reconstitution & Storage||Long term: -20°C; Short term: -20°C|
|Precautions||SERPINC1 / Antithrombin III Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.|
|Cellular Location||Secreted, extracellular space.|
|Tissue Location||Found in plasma.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
Bock S.C.,et al.Nucleic Acids Res. 10:8113-8125(1982).
Chandra T.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:1845-1848(1983).
Tsuji H.,et al.(In) Yoshida T.O., Wilson J.M. (eds.);
Olds R.J.,et al.Biochemistry 32:4216-4224(1993).
Zhang C.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.