|Application ||WB, IHC-P, E, Flo|
|Calculated MW||17490 Da|
|Dilution||IHC-P (10 µg/ml)|
|Target/Specificity||Recognizes mouse Interleukin 17, a 32kDa disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217).|
|Reconstitution & Storage||Aliquot and store at -20°C. Minimize freezing and thawing.|
|Precautions||IL17 Antibody (clone TC11-18H10) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ligand for IL17RA (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (By similarity). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (By similarity).|
|Tissue Location||Restricted to a subset of activated T-cells.|
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