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ARL6IP5 Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | O75915 |
| Reactivity | Human, Monkey |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 22kDa |
| Dilution | ELISA (1:32000), IHC-P (3.75 µg/ml), WB (1:32000) |
| Gene ID | 10550 |
|---|---|
| Other Names | PRA1 family protein 3, ADP-ribosylation factor-like protein 6-interacting protein 5, ARL-6-interacting protein 5, Aip-5, Cytoskeleton-related vitamin A-responsive protein, Dermal papilla-derived protein 11, GTRAP3-18, Glutamate transporter EAAC1-interacting protein, JM5, Prenylated Rab acceptor protein 2, Protein JWa, Putative MAPK-activating protein PM27, ARL6IP5, DERP11, JWA, PRA2, PRAF3 |
| Target/Specificity | Human ARL6IP5 / JWA. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | ARL6IP5 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ARL6IP5 |
|---|---|
| Synonyms | DERP11, JWA, PRA2, PRAF3 |
| Function | Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity- dependent manner. Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum. |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9ES40}; Multi-pass membrane protein. Cell membrane {ECO:0000250|UniProtKB:Q9ES40}; Multi-pass membrane protein. Cytoplasm {ECO:0000250|UniProtKB:Q9ES40}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9ES40}. Note=Also exists as a soluble form in the cytoplasm. Associated with microtubules {ECO:0000250|UniProtKB:Q9ES40} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic (By similarity).
References
Ikemoto M.J.,et al.NeuroReport 13:2079-2084(2002).
Schweneker M.,et al.FEBS Lett. 579:1751-1758(2005).
Ikeda A.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Zhou J.W.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
Zhang X.N.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
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