SNX16 Antibody (N-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P57768 |
Reactivity | Human, Mouse, Rat, Rabbit, Hamster, Monkey, Horse, Dog |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 39kDa |
Dilution | ELISA (1:64000), IHC-P (3.75 µg/ml), WB (1:64000) |
Gene ID | 64089 |
---|---|
Other Names | Sorting nexin-16, SNX16 |
Target/Specificity | Human SNX16. This antibody is expected to recognise both isoform a (NP_071416.2; NP_690049.1) and isoform b (NP_690050.1). |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | SNX16 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SNX16 |
---|---|
Function | May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm. |
Cellular Location | Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Lysosome |
Tissue Location | Detected in placenta, lung, liver,heart and pancreas. |
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Background
May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm.
References
Hanson B.J.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Nusbaum C.,et al.Nature 439:331-335(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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