|Application ||IHC-P, E|
|Dilution||ELISA (1:16000), IHC-P (3.75 µg/ml),|
|Other Names||Limbin, Ellis-van Creveld syndrome protein 2, EVC2, EVC2, LBN|
|Target/Specificity||Human EVC2. This antibody is expected to recognise isoform 1 (NP_667338.3) and isoform 2 (NP_001159608.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||EVC2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Positive regulator of the hedgehog signaling pathway (By similarity). Plays a critical role in bone formation and skeletal development.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Cell projection, cilium membrane Nucleus|
|Tissue Location||Found in the heart, placenta, lung, liver, skeletal muscle, kidney and pancreas|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Positive regulator of the hedgehog signaling pathway (By similarity). Plays a critical role in bone formation and skeletal development.
Takeda H.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:10549-10554(2002).
Ruiz-Perez V.L.,et al.Am. J. Hum. Genet. 72:728-732(2003).
Galdzicka M.,et al.Mol. Genet. Metab. 77:291-295(2002).
Ye X.,et al.Hum. Genet. 119:199-205(2006).
Sjoeblom T.,et al.Science 314:268-274(2006).
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