|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Hamster, Monkey, Chicken, Horse, Xenopus, Bovine, Dog|
|Dilution||ELISA (1:16000), IHC-P (6.25 µg/ml), WB (0.5-2 µg/ml)|
|Other Names||Tripartite motif-containing protein 2, 6.3.2.-, E3 ubiquitin-protein ligase TRIM2, RING finger protein 86, TRIM2, KIAA0517, RNF86|
|Target/Specificity||Human TRIM2 / RNF86. This antibody is expected to recognise both reported isoforms (NP_056086.2; NP_001123539.1). Cross-reactivity with TRIM3 has been demonstrated.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||KIAA0517 / TRIM2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance.
Reymond A.,et al.EMBO J. 20:2140-2151(2001).
Nagase T.,et al.DNA Res. 5:31-39(1998).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.