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KIAA0517 / TRIM2 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • WB - KIAA0517 / TRIM2 Antibody (C-Terminus) ALS13716
    TRIM2 antibody (0.5 ug/ml) staining of Rat Brain lysate (35 ug protein/ml in RIPA buffer).
  • IHC - KIAA0517 / TRIM2 Antibody (C-Terminus) ALS13716
    Anti-TRIM2 / RNF86 antibody IHC of human brain, cortex.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9C040
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Hamster, Monkey, Chicken, Horse, Xenopus, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 82kDa
Dilution ELISA (1:16000), IHC-P (6.25 µg/ml), WB (0.5-2 µg/ml)
Additional Information
Gene ID 23321
Other Names Tripartite motif-containing protein 2, 6.3.2.-, E3 ubiquitin-protein ligase TRIM2, RING finger protein 86, TRIM2, KIAA0517, RNF86
Target/Specificity Human TRIM2 / RNF86. This antibody is expected to recognise both reported isoforms (NP_056086.2; NP_001123539.1). Cross-reactivity with TRIM3 has been demonstrated.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsKIAA0517 / TRIM2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRIM2
Synonyms KIAA0517, RNF86
Function UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Background

UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance.

References

Reymond A.,et al.EMBO J. 20:2140-2151(2001).
Nagase T.,et al.DNA Res. 5:31-39(1998).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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$ 395.00
Cat# ALS13716
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