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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   MYRIP Antibody (C-Terminus)   

MYRIP Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • IHC - MYRIP Antibody (C-Terminus) ALS13718
    Anti-MYRIP antibody IHC of human brain, cortex.
  • IHC - MYRIP Antibody (C-Terminus) ALS13718
    Anti-MYRIP antibody IHC of human breast.
  • IHC - MYRIP Antibody (C-Terminus) ALS13718
    Anti-MYRIP antibody IHC of human colon, submucosal plexus.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q8NFW9
Reactivity Human, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 96kDa
Dilution ELISA (1:64000), IHC-P (3.75 µg/ml), WB (1:64000)
Additional Information
Gene ID 25924
Other Names Rab effector MyRIP, Exophilin-8, Myosin-VIIa- and Rab-interacting protein, Synaptotagmin-like protein lacking C2 domains C, SlaC2-c, Slp homolog lacking C2 domains c, MYRIP, SLAC2C
Target/Specificity Human MYRIP.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsMYRIP Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYRIP
Synonyms SLAC2C
Function Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q8K3I4}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q7TNY7} Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:Q7TNY7}. Note=In presynaptic and postsynaptic areas in photoreceptor cells and in the basal microvilli of retinal pigment epithelium cells. Associated with melanosomes. Colocalizes with actin filaments {ECO:0000250|UniProtKB:Q7TNY7}
Tissue Location Detected in brain, skin, heart, adrenal medulla, pancreas, intestine, liver, kidney, muscle and testis
Research Areas
Citations (0)

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Background

Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity).

References

El-Amraoui A.,et al.EMBO Rep. 3:463-470(2002).
Fukuda M.,et al.J. Biol. Chem. 277:43096-43103(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS13718
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