|Application ||WB, IHC-P, IF, ICC|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Nuclear pore complex protein Nup107, 107 kDa nucleoporin, Nucleoporin Nup107, NUP107|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||NUP107 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC.|
|Cellular Location||Nucleus membrane Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755)|
|Tissue Location||Ubiquitously expressed in fetal and adult tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC.
Cordes V.C.,et al.Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Belgareh N.,et al.J. Cell Biol. 154:1147-1160(2001).
Vasu S.,et al.J. Cell Biol. 155:339-354(2001).
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