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KDM3B / JMJD1B Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | Q7LBC6 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 192kDa |
| Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
| Gene ID | 51780 |
|---|---|
| Other Names | Lysine-specific demethylase 3B, 1.14.11.-, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCA, KDM3B, C5orf7, JHDM2B, JMJD1B, KIAA1082 |
| Target/Specificity | Human JMJD1B |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | KDM3B / JMJD1B Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KDM3B |
|---|---|
| Synonyms | C5orf7, JHDM2B, JMJD1B, KIAA1082 |
| Function | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. |
| Cellular Location | Nucleus. |
| Tissue Location | Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver. |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
References
Lai F.,et al.Genomics 70:123-130(2000).
Hu Z.,et al.Oncogene 20:6946-6954(2001).
Kikuno R.,et al.DNA Res. 6:197-205(1999).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Schmutz J.,et al.Nature 431:268-274(2004).
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