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KDM3B / JMJD1B Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IF - KDM3B / JMJD1B Antibody (Internal) ALS13764
    Immunofluorescence of JMJD1B in rat liver tissue with JMJD1B antibody at 20 ug/ml.
  • WB - KDM3B / JMJD1B Antibody (Internal) ALS13764
    Western blot of JMJD1B in rat liver tissue lysate with JMJD1B antibody at (A) 1 and (B) 2 ug/ml.
  • IHC - KDM3B / JMJD1B Antibody (Internal) ALS13764
    Anti-KDM3B / JMJD1B antibody IHC of human tonsil.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q7LBC6
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 192kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 51780
Other Names Lysine-specific demethylase 3B, 1.14.11.-, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCA, KDM3B, C5orf7, JHDM2B, JMJD1B, KIAA1082
Target/Specificity Human JMJD1B
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsKDM3B / JMJD1B Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KDM3B
Synonyms C5orf7, JHDM2B, JMJD1B, KIAA1082
Function Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
Cellular Location Nucleus.
Tissue Location Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver
Volume 50 µl
Research Areas
Citations (0)

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Background

Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.

References

Lai F.,et al.Genomics 70:123-130(2000).
Hu Z.,et al.Oncogene 20:6946-6954(2001).
Kikuno R.,et al.DNA Res. 6:197-205(1999).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Schmutz J.,et al.Nature 431:268-274(2004).

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$ 395.00
Cat# ALS13764
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