|Application ||WB, IHC-P|
|Dilution||IHC-P (5 µg/ml), WB (1:500-1:3000),|
|Other Names||Peptidyl-prolyl cis-trans isomerase FKBP3, PPIase FKBP3, 22.214.171.124, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-25, FK506-binding protein 3, FKBP-3, Immunophilin FKBP25, Rapamycin-selective 25 kDa immunophilin, Rotamase, FKBP3, FKBP25|
|Target/Specificity||Human FKBP25. Predicted cross-reactivity based on amino acid sequence homology: mouse (93%), rat (94%), bovine (97%).|
|Reconstitution & Storage||Aliquot and store at -20°C. Minimize freezing and thawing.|
|Precautions||FKBP25 / FKBP3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.|
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Provided below are standard protocols that you may find useful for product applications.
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
Wiederrecht G.,et al.Biochem. Biophys. Res. Commun. 185:298-303(1992).
Hung D.T.,et al.Biochem. Biophys. Res. Commun. 184:733-738(1992).
Jin Y.-J.,et al.J. Biol. Chem. 267:10942-10945(1992).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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