|Application ||WB, IHC-P|
|Dilution||IHC-P (5 µg/ml), WB (1:500-1:3000),|
|Other Names||Peptidyl-prolyl cis-trans isomerase FKBP3, PPIase FKBP3, 22.214.171.124, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-25, FK506-binding protein 3, FKBP-3, Immunophilin FKBP25, Rapamycin-selective 25 kDa immunophilin, Rotamase, FKBP3, FKBP25|
|Target/Specificity||Human FKBP25. Predicted cross-reactivity based on amino acid sequence homology: mouse (93%), rat (94%), bovine (97%).|
|Reconstitution & Storage||Aliquot and store at -20°C. Minimize freezing and thawing.|
|Precautions||FKBP25 / FKBP3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
Wiederrecht G.,et al.Biochem. Biophys. Res. Commun. 185:298-303(1992).
Hung D.T.,et al.Biochem. Biophys. Res. Commun. 184:733-738(1992).
Jin Y.-J.,et al.J. Biol. Chem. 267:10942-10945(1992).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.