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NDUFAF2 / NDUFA12L Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - NDUFAF2 / NDUFA12L Antibody (C-Terminus) ALS13781
    Immunofluorescence of Mimitin in Raji cells with Mimitin antibody at 20 ug/ml.
    detail
  • WB - NDUFAF2 / NDUFA12L Antibody (C-Terminus) ALS13781
    Western blot of Mimitin in Raji cell lysate with Mimitin antibody at (A) 1 and (B) 2 ug/ml.
    detail
  • IHC - NDUFAF2 / NDUFA12L Antibody (C-Terminus) ALS13781
    Anti-NDUFAF2 antibody IHC of human heart.
    detail
  • IHC - NDUFAF2 / NDUFA12L Antibody (C-Terminus) ALS13781
    Anti-NDUFAF2 antibody IHC of human liver.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q8N183
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 20kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 91942
Other Names Mimitin, mitochondrial, B17.2-like, B17.2L, Myc-induced mitochondrial protein, MMTN, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2, NDUFA12-like protein, NDUFAF2, NDUFA12L
Target/Specificity Human NDUFAF2
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsNDUFAF2 / NDUFA12L Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NDUFAF2
Synonyms NDUFA12L
Function Acts as a molecular chaperone for mitochondrial complex I assembly (PubMed:16200211, PubMed:19384974). Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:16200211, PubMed:27626371).
Cellular Location Mitochondrion.
Tissue Location Highly expressed in ESCC cells. Also expressed in heart, skeletal muscle, liver, and in fibroblasts
Research Areas
Citations (0)
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Background

Acts as a molecular chaperone for mitochondrial complex I assembly.

References

Tsuneoka M.,et al.J. Biol. Chem. 280:19977-19985(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Ogilvie I.,et al.J. Clin. Invest. 115:2784-2792(2005).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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Discontinued
Cat# ALS13781
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