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OCIAD1 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - OCIAD1 Antibody (C-Terminus) ALS13782
    Immunofluorescence of OCIAD1 in 293 cells with OCIAD1 antibody at 20 ug/ml.
    detail
  • IHC - OCIAD1 Antibody (C-Terminus) ALS13782
    Anti-OCIAD1 antibody IHC of human brain, cerebellum.
    detail
  • IHC - OCIAD1 Antibody (C-Terminus) ALS13782
    Anti-OCIAD1 antibody IHC of human prostate.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q9NX40
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 28kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 54940
Other Names OCIA domain-containing protein 1, Ovarian carcinoma immunoreactive antigen, OCIAD1, OCIA
Target/Specificity Human OCIAD1
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsOCIAD1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OCIAD1 (HGNC:16074)
Function Maintains stem cell potency (By similarity). Increases STAT3 phosphorylation and controls ERK phosphorylation (By similarity). May act as a scaffold, increasing STAT3 recruitment onto endosomes (By similarity). Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer (PubMed:20515946).
Cellular Location Endosome {ECO:0000250|UniProtKB:Q9CRD0}.
Tissue Location Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord
Research Areas
Citations (0)
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References

Luo L.Y.,et al.Biochem. Biophys. Res. Commun. 280:401-406(2001).
Xu X.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Li W.B.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).

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Discontinued
Cat# ALS13782
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