|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (3 µg/ml), WB (1-2 µg/ml),|
|Other Names||Receptor expression-enhancing protein 3, REEP3, C10orf74|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||REEP3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in circumvallate papillae.|
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Provided below are standard protocols that you may find useful for product applications.
Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes.
Saito H.,et al.Cell 119:679-691(2004).
Deloukas P.,et al.Nature 429:375-381(2004).
Castermans D.,et al.Eur. J. Hum. Genet. 15:422-431(2007).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Rigbolt K.T.,et al.Sci. Signal. 4:RS3-RS3(2011).
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