ZSCAN4 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | Q8NAM6 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 49kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 201516 |
---|---|
Other Names | Zinc finger and SCAN domain-containing protein 4, Zinc finger protein 494, ZSCAN4, ZNF494 |
Target/Specificity | Human ZSCAN4 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | ZSCAN4 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ZSCAN4 |
---|---|
Synonyms | ZNF494 |
Function | Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}. Chromosome, telomere |
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Provided below are standard protocols that you may find useful for product applications.
Background
Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity).
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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