SEC16B Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
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Primary Accession | Q96JE7 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 117kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 89866 |
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Other Names | Protein transport protein Sec16B, Leucine zipper transcription regulator 2, Regucalcin gene promoter region-related protein p117, RGPR-p117, SEC16 homolog B, SEC16B, KIAA1928, LZTR2, RGPR, SEC16S |
Target/Specificity | Human SEC16B |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | SEC16B Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SEC16B |
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Synonyms | KIAA1928, LZTR2, RGPR, SEC16S |
Function | Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:17192411, PubMed:21768384, PubMed:22355596). Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes (PubMed:21768384). |
Cellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Note=Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). |
Tissue Location | Ubiquitous. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization.
References
Misawa H.,et al.Int. J. Mol. Med. 8:513-520(2001).
Bhattacharyya D.,et al.Mol. Biol. Cell 18:839-849(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Misawa H.,et al.J. Cell. Biochem. 87:188-193(2002).
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