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SEC16B Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - SEC16B Antibody (C-Terminus) ALS13812
    Immunofluorescence of LZTR2 in mouse kidney tissue with LZTR2 antibody at 20 ug/ml.
    detail
  • WB - SEC16B Antibody (C-Terminus) ALS13812
    Western blot analysis of LZTR2 in mouse kidney tissue lysate with LZTR2 antibody at 1 ug/ml.
    detail
  • IHC - SEC16B Antibody (C-Terminus) ALS13812
    Anti-SEC16B antibody IHC of human kidney.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q96JE7
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 117kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 89866
Other Names Protein transport protein Sec16B, Leucine zipper transcription regulator 2, Regucalcin gene promoter region-related protein p117, RGPR-p117, SEC16 homolog B, SEC16B, KIAA1928, LZTR2, RGPR, SEC16S
Target/Specificity Human SEC16B
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsSEC16B Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEC16B
Synonyms KIAA1928, LZTR2, RGPR, SEC16S
Function Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:17192411, PubMed:21768384, PubMed:22355596). Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes (PubMed:21768384).
Cellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Note=Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER).
Tissue Location Ubiquitous.
Research Areas
Citations (0)
citation

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Background

Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization.

References

Misawa H.,et al.Int. J. Mol. Med. 8:513-520(2001).
Bhattacharyya D.,et al.Mol. Biol. Cell 18:839-849(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Misawa H.,et al.J. Cell. Biochem. 87:188-193(2002).

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$ 467.50
Cat# ALS13812
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