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>   home   >   Products   >   Primary Antibodies   >   BRIP1 / BACH1 Antibody (aa1233-1249)   

BRIP1 / BACH1 Antibody (aa1233-1249)

Rabbit Polyclonal Antibody

     
  • IHC - BRIP1 / BACH1 Antibody (aa1233-1249) ALS13819
    Anti-BRIP1 / FANCJ antibody IHC of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9BX63
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 141kDa
Dilution IHC-P (10 µg/ml), WB (1:500-1:1000),
Additional Information
Gene ID 83990
Other Names Fanconi anemia group J protein, Protein FACJ, 3.6.4.13, ATP-dependent RNA helicase BRIP1, BRCA1-associated C-terminal helicase 1, BRCA1-interacting protein C-terminal helicase 1, BRCA1-interacting protein 1, BRIP1, BACH1, FANCJ
Target/Specificity Residues 1233-1249 [NFKPSPSKNKGMFPGFK] of the human BACH1 protein
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsBRIP1 / BACH1 Antibody (aa1233-1249) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BRIP1
Synonyms BACH1, FANCJ
Function DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed, with highest levels in testis.
Citations (0)

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Background

DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.

References

Cantor S.B.,et al.Cell 105:149-160(2001).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Yu X.,et al.Science 302:639-642(2003).
Cantor S.B.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:2357-2362(2004).

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$ 395.00
Cat# ALS13819
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