|Application ||WB, IHC-P, E|
|Dilution||IHC-P (10 µg/ml), WB (1:500-1:1000),|
|Other Names||Fanconi anemia group J protein, Protein FACJ, 18.104.22.168, ATP-dependent RNA helicase BRIP1, BRCA1-associated C-terminal helicase 1, BRCA1-interacting protein C-terminal helicase 1, BRCA1-interacting protein 1, BRIP1, BACH1, FANCJ|
|Target/Specificity||Residues 1233-1249 [NFKPSPSKNKGMFPGFK] of the human BACH1 protein|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||BRIP1 / BACH1 Antibody (aa1233-1249) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.|
|Tissue Location||Ubiquitously expressed, with highest levels in testis.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.
Cantor S.B.,et al.Cell 105:149-160(2001).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Yu X.,et al.Science 302:639-642(2003).
Cantor S.B.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:2357-2362(2004).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.