|Reactivity||Human, Mouse, Rat, Rabbit, Monkey, Horse, Bovine, Dog|
|Dilution||IHC-P (3.75-7.5 µg/ml)|
|Other Names||Sorting nexin-4, SNX4|
|Target/Specificity||Human SNX4. A phox (PX) domain protein. In mouse, there is also a hypothetical protein called similar to SNX4 (XP_123014.1), which is virtually identical to SNX4.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||SNX4 Antibody (aa438-450) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation.|
|Cellular Location||Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Also detected on a juxtanuclear endocytic recycling compartment (ERC)|
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May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation.
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Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Traer C.J.,et al.Nat. Cell Biol. 9:1370-1380(2007).
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