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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   NTN1 / Netrin 1 Antibody (aa498-509)   

NTN1 / Netrin 1 Antibody (aa498-509)

Goat Polyclonal Antibody

     
  • IHC - NTN1 / Netrin 1 Antibody (aa498-509) ALS13838
    Anti-Netrin 1 antibody IHC of human brain, cortex.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession O95631
Reactivity Human, Mouse, Rat, Hamster, Monkey, Pig, Horse, Bovine
Host Goat
Clonality Polyclonal
Calculated MW 68kDa
Dilution IHC-P (3.75-7.5 µg/ml)
Additional Information
Gene ID 9423
Other Names Netrin-1, Epididymis tissue protein Li 131P, NTN1, NTN1L
Target/Specificity Human NTN1 / Netrin 1.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsNTN1 / Netrin 1 Antibody (aa498-509) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NTN1
Synonyms NTN1L
Function Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Widely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas Expressed in epididymis (at protein level)
Research Areas
Citations (0)

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Background

Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.

References

Meyerhardt J.A.,et al.Cell Growth Differ. 10:35-42(1999).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Li J.,et al.Mol. Cell. Proteomics 9:2517-2528(2010).
Mazelin L.,et al.Nature 431:80-84(2004).
Liu G.,et al.Proc. Natl. Acad. Sci. U.S.A. 106:2951-2956(2009).

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$ 395.00
Cat# ALS13838
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