|Reactivity||Human, Mouse, Rat, Monkey, Pig, Bovine|
|Dilution||IHC-P (3.75-7.5 µg/ml)|
|Other Names||EH domain-containing protein 1, PAST homolog 1, hPAST1, Testilin, EHD1, PAST, PAST1|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||Testilin / EHD1 Antibody (aa2-15) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Plays a role in myoblast fusion. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth.|
|Cellular Location||Recycling endosome membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Preferentially associates with tubular recycling endosomes. Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes|
|Tissue Location||Highly expressed in testis.|
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Provided below are standard protocols that you may find useful for product applications.
Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Plays a role in myoblast fusion. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth.
Guru S.C.,et al.Genome Res. 7:725-735(1997).
Mintz L.,et al.Genomics 59:66-76(1999).
Zhou J.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
Naslavsky N.,et al.Mol. Biol. Cell 15:2410-2422(2004).
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