|Dilution||IHC-P (3.75-7.5 µg/ml)|
|Other Names||Hyaluronidase-2, Hyal-2, 220.127.116.11, Hyaluronoglucosaminidase-2, Lung carcinoma protein 2, LuCa-2, HYAL2, LUCA2|
|Target/Specificity||Human HYAL2. Reported variants NP_003764 and NP_149348 represent identical proteins.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||HYAL2 Antibody (aa2-12) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
|Tissue Location||Widely expressed. No expression detected in adult brain.|
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Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R.
Lepperdinger G.,et al.J. Biol. Chem. 273:22466-22470(1998).
Chen J.,et al.Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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