HNF1A / HNF1 Antibody (aa617-631)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P20823 |
Reactivity | Human, Mouse, Rat, Hamster, Pig, Horse, Dog |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 67kDa |
Dilution | IHC-P (3.75-7.5 µg/ml) |
Gene ID | 6927 |
---|---|
Other Names | Hepatocyte nuclear factor 1-alpha, HNF-1-alpha, HNF-1A, Liver-specific transcription factor LF-B1, LFB1, Transcription factor 1, TCF-1, HNF1A, TCF1 |
Target/Specificity | Human HNF1A / TCF1. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | HNF1A / HNF1 Antibody (aa617-631) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HNF1A |
---|---|
Synonyms | TCF1 |
Function | Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (By similarity). Binds to the inverted palindrome 5'- GTTAATNATTAAC-3' (PubMed:12453420, PubMed:10966642). Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:10966642} |
Tissue Location | Liver. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5'- GTTAATNATTAAC-3'.
References
Bach I.,et al.Genomics 8:155-164(1990).
Bach I.,et al.EMBO J. 12:4229-4242(1993).
Yamagata K.,et al.Nature 384:455-458(1996).
Yang C.-W.,et al.Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
Gonzalez Ruano E.,et al.Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.