|Reactivity||Human, Mouse, Rat, Hamster, Monkey, Chicken, Horse, Xenopus, Bovine, Dog|
|Dilution||IHC-P (3.75-7.5 µg/ml)|
|Other Names||Glutamate receptor ionotropic, NMDA 2A, GluN2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, hNR2A, GRIN2A, NMDAR2A|
|Target/Specificity||Human GRIN2A / NMDAR2A.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||GRIN2A / NMDAR2A / NR2A Antibody (aa875-885) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
Foldes R.L.,et al.Biochim. Biophys. Acta 1223:155-159(1994).
Hess S.D.,et al.J. Pharmacol. Exp. Ther. 278:808-816(1996).
Martin J.,et al.Nature 432:988-994(2004).
Endele S.,et al.Nat. Genet. 42:1021-1026(2010).
Wei X.,et al.Nat. Genet. 43:442-446(2011).
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