|Reactivity||Human, Rabbit, Monkey, Horse, Dog|
|Dilution||IHC-P (3.75-7.5 µg/ml)|
|Other Names||Orexin receptor type 2, Ox-2-R, Ox2-R, Ox2R, Hypocretin receptor type 2, HCRTR2|
|Target/Specificity||Human HCRTR2 / Orexin Receptor 2.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||OX2R / Orexin Receptor 2 Antibody (aa390-402) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).|
|Cellular Location||Cell membrane; Multi- pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.
Sakurai T.,et al.Cell 92:573-585(1998).
Olafsdottir B.R.,et al.Neurology 57:1896-1899(2001).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Hungs M.,et al.Bioessays 23:397-408(2001).
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