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Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q13621 |
| Reactivity | Human, Monkey |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 121kDa |
| Dilution | IHC-P (3.75-7.5 µg/ml) |
| Gene ID | 6557 |
|---|---|
| Other Names | Solute carrier family 12 member 1, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2, Kidney-specific Na-K-Cl symporter, SLC12A1, NKCC2 |
| Target/Specificity | Human SLC12A1. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | SLC12A1 / NKCC2 Antibody (aa43-57) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC12A1 |
|---|---|
| Synonyms | NKCC2 |
| Function | Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume. |
| Cellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Location | Kidney specific. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
References
Simon D.B.,et al.Nat. Genet. 13:183-188(1996).
Di Fulvio M.,et al.Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
Zody M.C.,et al.Nature 440:671-675(2006).
Cruz-Rangel S.,et al.Am. J. Physiol. 301:C601-C608(2011).
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