|Dilution||IHC-P (3.75-7.5 µg/ml)|
|Other Names||Solute carrier family 12 member 1, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2, Kidney-specific Na-K-Cl symporter, SLC12A1, NKCC2|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||SLC12A1 / NKCC2 Antibody (aa43-57) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Kidney specific.|
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Provided below are standard protocols that you may find useful for product applications.
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
Simon D.B.,et al.Nat. Genet. 13:183-188(1996).
Di Fulvio M.,et al.Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
Zody M.C.,et al.Nature 440:671-675(2006).
Cruz-Rangel S.,et al.Am. J. Physiol. 301:C601-C608(2011).
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