|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Protein NLRC3, CARD15-like protein, Caterpiller protein 16.2, CLR16.2, Nucleotide-binding oligomerization domain protein 3, NLRC3, NOD3|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||NOD3 / NLRC3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May modulate T-cell activation. Decreases the transcription of genes that are normally up-regulated after T-cell stimulation. Delays degradation of NFKBIA/IKBA.|
|Tissue Location||Detected in peripheral blood mononuclear cells.|
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May modulate T-cell activation. Decreases the transcription of genes that are normally up-regulated after T-cell stimulation. Delays degradation of NFKBIA/IKBA.
Inohara N.,et al.Nat. Rev. Immunol. 3:371-382(2003).
Conti B.J.,et al.J. Biol. Chem. 280:18375-18385(2005).
Jikuya H.,et al.DNA Res. 10:49-57(2003).
Jikuya H.,et al.Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Huse K.,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
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