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NLRP7 / NALP7 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - NLRP7 / NALP7 Antibody (N-Terminus) ALS13987
    Immunofluorescence of NALP7 in human brain tissue with NALP7 antibody at 20 ug/ml.
    detail
  • IHC - NLRP7 / NALP7 Antibody (N-Terminus) ALS13987
    Anti-NLRP7 antibody IHC of human spleen.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q8WX94
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 112kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 199713
Other Names NACHT, LRR and PYD domains-containing protein 7, Nucleotide-binding oligomerization domain protein 12, PYRIN-containing APAF1-like protein 3, NLRP7, NALP7, NOD12, PYPAF3
Target/Specificity Human NLRP7
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsNLRP7 / NALP7 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NLRP7
Synonyms NALP7, NOD12, PYPAF3
Function Inhibits CASP1/caspase-1-dependent IL1B secretion.
Tissue Location Expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. Not detected in skeletal muscle.
Research Areas
Citations (0)
citation

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Background

Inhibits CASP1/caspase-1-dependent IL1B secretion.

References

Wang L.,et al.J. Biol. Chem. 277:29874-29880(2002).
Tschopp J.,et al.Nat. Rev. Mol. Cell Biol. 4:95-104(2003).
Grimwood J.,et al.Nature 428:529-535(2004).
Inohara N.,et al.Nat. Rev. Immunol. 3:371-382(2003).
Kinoshita T.,et al.J. Biol. Chem. 280:21720-21725(2005).

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$ 467.50
Cat# ALS13987
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