|Application ||WB, IHC-P, IF, E|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||NACHT, LRR and PYD domains-containing protein 7, Nucleotide-binding oligomerization domain protein 12, PYRIN-containing APAF1-like protein 3, NLRP7, NALP7, NOD12, PYPAF3|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||NLRP7 / NALP7 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||NALP7, NOD12, PYPAF3|
|Function||Inhibits CASP1/caspase-1-dependent IL1B secretion.|
|Tissue Location||Expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. Not detected in skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
Inhibits CASP1/caspase-1-dependent IL1B secretion.
Wang L.,et al.J. Biol. Chem. 277:29874-29880(2002).
Tschopp J.,et al.Nat. Rev. Mol. Cell Biol. 4:95-104(2003).
Grimwood J.,et al.Nature 428:529-535(2004).
Inohara N.,et al.Nat. Rev. Immunol. 3:371-382(2003).
Kinoshita T.,et al.J. Biol. Chem. 280:21720-21725(2005).
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