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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   TFPI / LACI Antibody   

TFPI / LACI Antibody

Mouse Monoclonal Antibody

     
  • IHC - TFPI / LACI Antibody ALS13989
    Anti-TFPI antibody IHC of human vessel.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P10646
Reactivity Human
Host Mouse
Clonality Monoclonal
Calculated MW 35kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 7035
Other Names Tissue factor pathway inhibitor, TFPI, Extrinsic pathway inhibitor, EPI, Lipoprotein-associated coagulation inhibitor, LACI, TFPI, LACI, TFPI1
Target/Specificity Recognizes Human Tissue Factor Pathway Inhibitor.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsTFPI / LACI Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TFPI
Synonyms LACI, TFPI1
Function Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Cellular Location Isoform Alpha: Secreted.
Tissue Location Mostly in endothelial cells.
Research Areas
Citations (0)

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Background

Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

References

Wun T.-C.,et al.J. Biol. Chem. 263:6001-6004(1988).
Girard T.J.,et al.Thromb. Res. 55:37-50(1989).
van der Logt C.P.E.,et al.Biochemistry 30:1571-1577(1991).
Girard T.J.,et al.J. Biol. Chem. 266:5036-5041(1991).
Chang J.-Y.,et al.Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS13989
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